Upcoming Lunch Seminar with Prof. Wendell Coltro
Please join Prof. Wendell K. T. Coltro of the Federal University of Goias, Brazil for his presentation “Microfluidic paper-based analytical devices: Do-it-yourself approaches” on Friday, October 18th from 12:30 to 1:30 pm in 3124 GLH. Lunch will be provided to those who RSVP here by October 16th.
Abstract: Microfluidic paper-based analytical devices (μPADs) have emerged as powerful platforms for analytical and bioanalytical chemistry, offering advantages over other substrate materials, including simpler fabrication protocols, compatibility with multi-purpose detectors, and global affordability. Alternative fabrication protocols involving “do-it-yourself” (DIY) approaches have been developed in our group to replace standard microfabrication methods. This presentation will present the design and construction of dual microfluidic paper-based analytical devices (dual-μPADs) as a lab-on-paper platform comprising a colorimetric and electrochemical module to obtain a dual-mode signal readout sensing strategy. A 3D pen polymeric resin was used to prepare graphite carbon-based electrodes and hydrophobic barriers on paper substrates. The proposed carbon-based ink was employed to manufacture electrodes on paper based on a stencil-printing approach, further characterized by electrochemical and morphological analyses. The analytical performance of the dual-μPADs was simultaneously evaluated for lactate, pH, nitrite, and salivary amylase (sAA) analysis. Other recently developed DIY protocols, including stencil printing and digitally controlled cutting printing fabrication protocols, will also be discussed as well as examples of bioanalytical applications.